Cobblestone Spine and Joint Institute

Cobblestone Spine and Joint Institute is a chiropractic and non-surgical spine and joint clinic in Royal Palm Beach, Florida, that also offers regenerative and wellness services.

Clinicians

• Dean Mammales, DC — founder; chiropractor
• Yuleisy Coto, MSN, APRN, FNP-C — administers regenerative and wellness procedures

Regenerative treatments offered

• Platelet-rich plasma (PRP) — for joints, tendons and ligaments
• Stem cell therapy — described as ethically sourced, non-fetal stem cells, for advanced joint degeneration or where PRP alone is insufficient; the site cites Florida CS/CS/SB 1768
• Peptide therapy — BPC-157, TB-500, Sermorelin and CJC-1295/Ipamorelin, physician-supervised

Conditions the practice lists

For PRP: knee osteoarthritis, rotator cuff injuries, tennis elbow and plantar fasciitis. Stem cell therapy is listed for advanced joint degeneration.

What to know before you call

• New patients start with an exam; requests are confirmed within one business day.
• The site states United Healthcare and Medicare are accepted, with benefits verified before the visit; coverage of regenerative treatments is not stated.
• A payment plans page is available.

RPG verification notes

• Clinician names and credentials listed on the website
• Specific stem cell tissue source not named
• Prices not published

Last verified by Regen Provider Guide: October 2026. Confirm treatment details, candidacy, insurance coverage and costs directly with the practice. RPG makes no claim about the effectiveness of any treatment.