Upstate Regenerative Medicine

Upstate Regenerative Medicine is a physician-led orthobiologics practice in Greenville, South Carolina, that offers Regenexx procedures.

Clinicians

• Brian Jakubowicz, MD — double board certified in anesthesiology and pain medicine; pain medicine fellowship at Beth Israel Deaconess Medical Center

Regenerative treatments offered

• Bone marrow concentrate (Regenexx) — bone marrow harvested from the back of the hip and injected using image guidance
• Platelet-rich plasma (PRP)
• Regenexx platelet lysate procedure

Conditions the practice lists

The site lists osteoarthritis, joint injuries, spine pain, overuse conditions and sports injuries, with treatment pages for the knee, hip, shoulder and rotator cuff, hand and wrist (including the basal thumb joint), elbow, foot and ankle, spine and neck.

What to know before you call

• Phone shown: 864-998-8608; hours Monday to Friday, 8 AM to 5 PM
• The site offers an online candidate request form
• A physician reviews the patient’s condition and imaging to choose between bone marrow concentrate and a platelet-based treatment
• The practice also offers MLS laser therapy

RPG verification notes

• Board certification listed on the physician bio page
• Website states Regenexx procedures have a success and failure rate
• Prices and insurance statements not published
• No FDA disclaimer found

Last verified by Regen Provider Guide: October 2026. Confirm treatment details, candidacy, insurance coverage and costs directly with the practice. RPG makes no claim about the effectiveness of any treatment.